KEGG ORTHOLOGY: K10807

ORTHOLOGY: K10807

Entry

K10807                      KO

Symbol

RRM1

Name

ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]

Pathway

map00230

Purine metabolism

map00240

Pyrimidine metabolism

map00480

Glutathione metabolism

map00983

Drug metabolism - other enzymes

map01100

Metabolic pathways

map01232

Nucleotide metabolism

Module

M00053

Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP

M00938

Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Reaction

R02017

2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase

R02018

2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase

R02019

2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase

R02024

2'-deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase

R08363

2'-deoxyribonucleoside-diphosphate:tryparedoxin-disulfide 2'-oxidoreductase

R08364

2'-deoxyribonucleoside-diphosphate:trypanothione-disulfide 2'-oxidoreductase

R11893

5-fluorodeoxyuridine-diphosphate:thioredoxin-disulfide 2'-oxidoreductase

Disease

H01395

Autosomal recessive progressive external ophthalmoplegia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
   00240 Pyrimidine metabolism
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1

Other DBs

GO:

0004748

Genes

HSA:	6240(RRM1)

PTR:	450974(RRM1)

PPS:	100991648(RRM1)

GGO:	101129602(RRM1)

PON:	100172956(RRM1)

PPYG:

129008193(RRM1)

NLE:	100599741(RRM1)

HMH:	116476611(RRM1)

SSYN:

129484560(RRM1)

MCC:	717990(RRM1)

MCF:	102131278(RRM1)

MTHB:

126935035

MNI:	105468675(RRM1)

CSAB:

103247970(RRM1)

CATY:

105578816(RRM1)

PANU:

101021447(RRM1)

TGE:	112607414(RRM1)

MLEU:

105549258(RRM1)

RRO:	104665174(RRM1)

RBB:	108543724(RRM1)

TFN:	117079801(RRM1)

PTEH:

111540914(RRM1)

CANG:

105522325(RRM1)

CJC:	100385488(RRM1)

SBQ:	101047207(RRM1)

CIMI:

108307499(RRM1)

ANAN:

105720362(RRM1)

CSYR:

103276646(RRM1)

MMUR:

105860311(RRM1)

LCAT:

123642326(RRM1)

PCOQ:

105811479(RRM1)

OGA:	100949493(RRM1)

MMU:	20133(Rrm1)

MCAL:

110297993(Rrm1)

MPAH:

110332415(Rrm1)

RNO:	685579(Rrm1)

MCOC:

116102695(Rrm1)

ANU:	117713499(Rrm1)

ASYL:

127664185(Rrm1)

MUN:	110541570(Rrm1)

CGE:	100761591(Rrm1)

MAUA:

101826102(Rrm1)

PROB:

127228015(Rrm1)

PLEU:

114706610(Rrm1)

MORG:

121463953(Rrm1)

MFOT:

126488854

AAMP:

119824709(Rrm1)

NGI:	103750826(Rrm1)

HGL:	101708047(Rrm1)

CPOC:

100728488(Rrm1) 111754150

CCAN:

109681933(Rrm1)

DORD:

105984066(Rrm1)

DSP:	122115134(Rrm1)

PLOP:

125361919(Rrm1)

NCAR:

124960453

MMMA:

107135576(Rrm1)

ITI:	101960362(Rrm1)

OCU:

100345823

OPI:	101524574(RRM1)

TUP:	102488019(RRM1)

GVR:	103607698(RRM1)

CFA:	476823(RRM1)

CLUD:

112667484(RRM1)

VVP:	112928709(RRM1)

VLG:	121476512(RRM1)

NPO:	129506757(RRM1)

AML:	100472317(RRM1)

UMR:	103678102(RRM1)

UAH:	113269248(RRM1)

UAR:	123782522(RRM1)

ELK:

111159434

LLV:

125078953

MPUF:

101687386(RRM1)

MNP:	132023624(RRM1)

MLK:	131808217(RRM1)

NVS:	122912643(RRM1)

ORO:	101383805(RRM1)

EJU:	114218713(RRM1)

ZCA:	113914985(RRM1)

MLX:	118003890(RRM1)

NSU:	110593477(RRM1)

LWW:	102741658(RRM1)

FCA:	101097343(RRM1)

PYU:	121039212(RRM1)

PCOO:

112866168(RRM1)

PBG:	122483404(RRM1)

PVIV:

125177198(RRM1)

LRUF:

124505231

LGF:	123601234(RRM1)

AJU:

106966008

PTG:	102953329(RRM1)

PPAD:

109267118(RRM1)

PUC:

125937019

PLEZ:

122200058(RRM1)

HHV:	120245133(RRM1)

BTA:	505537(RRM1)

BOM:	102272609(RRM1)

BIU:	109569745(RRM1)

BBUB:

102401333(RRM1)

BBIS:

104995548(RRM1)

CHX:	102189416(RRM1)

OAS:	101116171(RRM1)

BTAX:

128060059(RRM1)

CSUM:

138092411(RRM1)

ODA:	120876704(RRM1)

CCAD:

122449759(RRM1)

MREE:

136174385(RRM1)

OVR:	110135804(RRM1)

MBEZ:

129554605(RRM1)

SSC:	102166900(RRM1)

CFR:	102514637(RRM1)

CBAI:

105083267(RRM1)

CDK:	105096519(RRM1)

VPC:	102540806(RRM1)

BACU:

103014342(RRM1)

BMUS:

118899367(RRM1)

LVE:	103086289(RRM1)

OOR:	101285550(RRM1)

LALB:

132526075(RRM1)

DLE:	111170548(RRM1)

PCAD:

102995944(RRM1)

PSIU:

116758138(RRM1)

NASI:

112390769(RRM1)

ECB:	100053126(RRM1)

EPZ:	103558527(RRM1)

EAI:	106831641(RRM1)

MYB:	102262075(RRM1)

MYD:	102756677(RRM1)

MMYO:

118664723(RRM1)

MLF:	102423105(RRM1)

MDT:	132240855(RRM1)

MYUM:

139017287(RRM1)

PKL:	118713432(RRM1)

EFUS:

103293552(RRM1)

MNA:	107544172(RRM1)

DRO:	112316008(RRM1)

SHON:

119002624(RRM1)

AJM:	119042096(RRM1)

PDIC:

114498637(RRM1)

PHAS:

123805596(RRM1)

MMF:	118627566(RRM1)

PPAM:

129076349(RRM1)

HAI:	109372434(RRM1)

RFQ:	117030370(RRM1)

PALE:

102879969(RRM1)

PGIG:

120590280(RRM1)

PVP:	105303696(RRM1)

RAY:	107517357(RRM1)

MJV:	108388557(RRM1)

TOD:	119255579(RRM1)

SARA:

101550021(RRM1)

SFUM:

130025063(RRM1)

SETR:

126018134(RRM1)

LAV:	100677500(RRM1)

TMU:

101347185

ETF:	101638702(RRM1)

DNM:	101419077 101424915(RRM1)

MDO:	100013713(RRM1)

GAS:	123238764(RRM1)

SHR:	100913408(RRM1)

AFZ:

127555272

PCW:	110195189(RRM1)

TVP:	118838917(RRM1)

PBRV:

138143469(RRM1)

OAA:	100073391(RRM1)

TACU:

119946518(RRM1)

GGA:	419081(RRM1)

PCOC:

116232705(RRM1)

MGP:	100545411(RRM1)

CJO:	107308587(RRM1)

TPAI:

128088582(RRM1)

LMUT:

125695599(RRM1)

NMEL:

110392111(RRM1)

APLA:

101796445 119716811

ACYG:

106048561(RRM1)

CATA:

118259763(RRM1)

AFUL:

116494370(RRM1)

TGU:	115497664(RRM1)

LSR:	110474947(RRM1)

SCAN:

103823822(RRM1)

PMOA:

120499995(RRM1)

OTC:	121334240(RRM1)

PRUF:

121355131(RRM1)

ATRC:

139591455(RRM1)

GFR:	102044314(RRM1)

FAB:	101812731(RRM1)

OMA:	130251859(RRM1)

PHI:	102102024(RRM1)

PMAJ:

107207454(RRM1)

CCAE:

111943781(RRM1)

CCW:	104698094(RRM1)

CBRC:

103621838(RRM1)

ACOE:

138104897(RRM1)

ETL:	114070910(RRM1)

ZAB:

102074186

ZLE:	135443856(RRM1)

ACHL:

103806720(RRM1)

SVG:	106861740(RRM1)

MMEA:

130582723(RRM1)

HRT:	120747859(RRM1)

SATI:

136358242(RRM1)

CCIC:

134058152(RRM1)

FPG:	101915772(RRM1)

FCH:	102046747(RRM1)

CCRI:

104159151(RRM1)

NNT:	104411606(RRM1)

SHAB:

115604317(RRM1)

ACUN:

113476025(RRM1)

TALA:

104355945(RRM1)

ACHC:

115353382(RRM1)

HALD:

104311412(RRM1)

HLE:	104837516(RRM1)

AGEN:

126048484

HHAR:

128153309(RRM1)

GCL:

127025327

LDI:	104347597(RRM1)

MNB:	103775486(RRM1)

DPUB:

104308962(RRM1)

PPUS:

135175813(RRM1)

AVIT:

104278809(RRM1)

BRHI:

104491086(RRM1)

EGZ:	104122179(RRM1)

NNI:	104014845(RRM1)

PCRI:

104031505(RRM1)

PCAO:

104041608(RRM1)

PADL:

103925511(RRM1)

AFOR:

103908490(RRM1)

FGA:	104079158(RRM1)

GSTE:

104259209(RRM1)

CLV:	102092480(RRM1)

MUI:	104537353(RRM1)

PGUU:

104458079(RRM1)

PLET:

104621896(RRM1)

CMAC:

104480954(RRM1)

CUCA:

104055945(RRM1)

TEO:	104373098(RRM1)

BREG:

104632334(RRM1)

OHA:	104339483(RRM1)

ACAR:

104517652(RRM1)

CPEA:

104398224(RRM1)

CVF:	104291581(RRM1)

RTD:	128913157(RRM1)

CRID:

134512794(RRM1)

AAM:	106489774(RRM1)

AROW:

112978639(RRM1)

NPD:	112954761(RRM1)

TGT:	104575426(RRM1)

DNE:	112993727(RRM1)

SCAM:

104141512(RRM1)

ASN:	102385541(RRM1)

AMJ:	102570766(RRM1)

CPOO:

109306869(RRM1)

GGN:	109303061(RRM1)

PSS:	102462750(RRM1)

CMY:	102936455(RRM1)

CCAY:

125631265(RRM1)

DCC:	119844641(RRM1)

CPIC:

101944456(RRM1)

TST:	117871366(RRM1)

CABI:

116817212(RRM1)

MRV:	120395561(RRM1)

ACS:	100562780(rrm1)

ASAO:

132770303(RRM1)

PVT:	110078155(RRM1)

SUND:

121926978(RRM1)

PBI:	103055237(RRM1)

PMUR:

107298422(RRM1)

CTIG:

120315049(RRM1)

TSR:	106556770(RRM1)

PGUT:

117676449(RRM1)

APRI:

131199464(RRM1)

PTEX:

113450433(RRM1)

NSS:	113427614(RRM1)

VKO:	123017342(RRM1)

PMUA:

114595152(RRM1)

PRAF:

128412037(RRM1)

ZVI:	118085579(RRM1)

HCG:	128351999(RRM1)

GJA:	107122175(RRM1)

STOW:

125431871(RRM1)

EMC:	129325737(RRM1)

XLA:	108710085(rrm1.S) 399431(rrm1.L)

XTR:	100145720(rrm1)

NPR:	108803090(RRM1)

BBUF:

120996630(RRM1)

BGAR:

122945033(RRM1)

PWL:	138249704(RRM1)

MUO:	115468265(RRM1)

GSH:	117362591(RRM1)

DRE:	30740(rrm1)

SRX:	107749935(rrm1)

SANH:

107673837 107684690

SGH:	107557082 107590092

CAUA:

113038442 113064032

CGIB:

127942045 127986385

PTET:

122326769(rrm1)

LROH:

127152879(rrm1)

OMC:	131528694(rrm1)

PPRM:

120494659(rrm1)

RKG:	130095351(rrm1)

MAMB:

125252685(rrm1)

CIDE:

127503842

CERY:

137012887(rrm1)

MASI:

127428994 127431150

TROS:

130548581 130570513(rrm1)

TDW:	130408329(rrm1)

MANU:

129423149(rrm1)

PDAB:

135776469(rrm1)

IPU:

108279224

IFU:	128622518(rrm1)

PHYP:

113541760(rrm1)

SMEO:

124398322(rrm1)

TFD:	113649147(rrm1)

TVC:	132859983(rrm1)

CGAR:

128507532(rrm1)

NGRA:

132895526(rrm1)

TRN:	134330409(rrm1)

AMEX:

103038586(rrm1)

CMAO:

118820338(rrm1)

EEE:	113573958(rrm1)

CHAR:

105889624(rrm1)

SPIL:

134072161(rrm1)

TRU:	101065684 101069675

TFS:	130534926 130537382

TNG:	GSTEN00014797G001 GSTEN00022159G001

LCO:	104919744 104931438

NCC:	104954681 104966767

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117260284 117262622

EFO:	125889283 125898128

PLEP:

121943545 121952332

SLUC:

116047711 116064736

ECRA:

117942309 117955188

ESP:	116677631 116700609

PFLV:

114553202 114567325

GAT:	120808701 120822018

PPUG:

119215118 119221091

AFB:	129112616 129113178

CLUM:

117741123 117742476

PSWI:

130188910 130210557

CANA:

137791043 137802183

CVE:	137872992 137876773

MSAM:

119883552 119895661

SCHU:

122879651 122888822

CUD:	121518719 121524518

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101476861 101481005

ONL:	100694900 100696561

OAU:	116323629 116330274

OLA:	101156188 101156995

OML:	112143015 112149636

CSAI:

133441780 133460293

XMA:	102224167 102229193

XCO:	114133288 114152927

XHE:	116707648 116728104

PRET:

103474651(rrm1) 103475859

PFOR:

103136300 103145622

PLAI:

106939252 106953358

PMEI:

106920178 106922180

GAF:	122833272 122844845

PPRL:

129368857 129369968

CVG:	107096864 107098236

CTUL:

119789586 119797348

GMU:	124876466 124884647

NFU:	107380274 107386517

KMR:	108240955 108248264

ALIM:

106516384 106527842

NWH:	119410628 119420142

AOCE:

111577631 111580584

EJA:	138195952 138197375

BFRE:

138625443 138637070

MCEP:

125013515 125020674

CSEM:

103378457 103395426

POV:	109628825 109630282

SSEN:

122773952 122780007

SSOE:

131458088 131462503

HHIP:

117772415 117773971

HSP:	118106369 118122692

PPLT:

128439941 128456674

SMAU:

118294455 118300560

LCF:	108894047 108900846

SDU:	111234317 111238155

SLAL:

111653898 111654130

XGL:	120792386 120802700

HCQ:	109512506 109526384

SSCV:

125972683(rrm1)

SBIA:

133505169(rrm1)

PEE:	133405267(rrm1)

PTAO:

133482760(rrm1)

BPEC:

110163552 110168084

MALB:

109974364(rrm1)

BSPL:

114868225 114869905

SJO:	128360682 128371111

SSCO:

133980783 133993747

GMH:	115547553 115561056

SASA:

100195484(rir1) 106567863

STRU:

115148980 115154439

OTW:	112228646 112257760

OMY:	110533741 110537378

OGO:	123999969 124009694

ONE:	115105642 115135824

OKI:	109875646 109892668

OKE:	118390178 118391243

OMM:	135548503 135550606

OCLA:

139418336 139423029

SALP:

111950589 111980701

SNH:	120045137 120057127

CCLU:

121573643 121580012

ELS:	105023907(rrm1)

SFM:	108921253(rrm1)

PKI:	111852165(rrm1)

AANG:

118236069(rrm1)

AROT:

135264127(rrm1)

CCOG:

133132538(rrm1)

LOC:	102699070(rrm1)

PSPA:

121302884(rrm1)

ARUT:

117405275 117972644

PSEX:

120523951(rrm1)

LCM:	102359247(RRM1)

CMK:	103191328(rrm1)

RTP:	109936713(rrm1)

CPLA:

122550984(rrm1)

HOC:	132816590(rrm1)

LERI:

129698341(rrm1)

PMRN:

116958382(RRM1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:	100373543(RRM1)

PFLL:

139131680

DME:	Dmel_CG5371(RnrL)

DER:

6541743

DSE:

6611964

DSI:	Dsimw501_GD22272(Dsim_GD22272)

DYA:	Dyak_GE26085

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18284

DAZ:

108609704

DNV:

108649554

DHE:

111597781

DVI:	6636907(RnrL)

CCAT:

101456426

BOD:

106627109

BDR:	105225087 125779622

RZE:

108378285

AOQ:	129247874 129249453

ALUD:

128864044 128864045

TDA:	119687779 119690168

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135963731(RnrL)

GFS:	119632567 119638893

ECOE:

129946423

CLON:

129608906

HIS:	119646829 119661431

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AALI:

ACOS:

AAG:	110680439 5573651

AALB:

109420799 109621992

ASUA:

134212281

CQU:	CpipJ_CPIJ005992

CPII:

120428020 120430583

CNS:	116343628 116346412

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:	114876318 114876477

OLG:

MGEN:

NMEA:

CGIG:

SOC:	105197671 105199909

MPHA:

105827880 105833086

AEC:	105147572 105148645

ACEP:

105623179 105624129

PBAR:

105422118 105423905

VEM:	105562394 105565944

COBS:

139104252 139107823

TLN:	139808885 139824082(Rnrl)

HST:	105183976 105189123

DQU:	106741072 106751956

CFO:	105251228 105257073

FEX:	115233067 115239344

PMEC:

138932152 138937351 138943375

LHU:	105670072 105670998 105679058(RnrL)

PGC:	109854085 109856119 109857092

OBO:	105276888 105284986

PCF:	106787688 106788628

PFUC:

122514114 122523829

VPS:	122632917 122634910

VCRB:

124428093 124430269

VVE:	124953016 124954013

NVI:	100113486 100116236

CSOL:

TPRE:

LHT:

LBD:

MDL:	103573895 103574941 106693104

CGLO:

123259783 123266983

FAS:	105271421 105271603

DAM:	107048023 107048026

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124214494(RnrL)

NFB:

NLO:

NVG:

AROA:

TCA:	657098 657179

TMOL:

138132972 138132999

DPA:

109535521

ESIM:

136413256(RnrL)

EFOR:

136343803(RnrL)

SOY:	115874541 115874542

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:	111510796 111510799

DVV:	114338204 114338205

NVL:	108559931 108565290

DCOR:

135792142(RnrL)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213673

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137933067(RnrL)

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:	114349888 114357256

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:	100161794 100162830 100166276 100569674 100573189 107884892

DNX:	107161542 107170541 107172287

AGS:	114127098 114129938 114129957

RMD:	113547936 113549848 113551011

ACOO:

126833305 126833958

DVT:	126906781 126906782

BTAB:

109036078

DCI:

103516780

CLEC:

106672623

HHAL:

106691597(RnrL)

NLU:	111045786 120355441

HVI:

124356673

MQU:

128985685

PHU:	Phum_PHUM350970

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

HAMR:

139691451(RnrL)

FCD:

110851853

DPX:	DAPPUDRAFT_302612

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:	128697529(RnrL)

PTRU:

123513977

ESN:

127007320

MNZ:

135224486

MRJ:	136844465(RnrL)

PORN:

139745778(RnrL)

HAZT:

108681036

EAF:

111696462

LSM:	121119207(RnrL)

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

113792415 113796683 113798110

DFR:	124489936 124494830

CSCU:

111623540 111639177

CVS:	136972305(RnrL) 136972316

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_T23G5.1(rnr-1)

CBR:	CBG_10154(Cbr-rnr-1)

CRQ:	GCK72_009383

NAI:	NECAME_14210

BMY:	BM_BM13811(Bma-rnr-1)

LOA:	LOAG_00652

TSP:

Tsp_11458

HRO:	HELRODRAFT_106206 HELRODRAFT_185290 HELRODRAFT_93558

LGI:	LOTGIDRAFT_206843

PVUL:

126830025

PCAN:

112560420

LSAX:

138954191 138957397 138968587

BGT:	106058807 106058826

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111124500 111127434

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106154653 106170045

SMM:	Smp_009030

OVI:	T265_03280

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_50804

AQU:

100638722

ATH:	AT2G21790(RNR1)

ALY:	9302917 9314640 9324272

CRB:	17880774 17890427

CSAT:

104713628 104716214 104720856 104751830 104757556 104757567

EUS:	EUTSA_v10000480mg EUTSA_v10024430mg EUTSA_v10027643mg

BRP:	103827773 103835128 103847573

BNA:	106361503 106381982 106419087 106448290 111198774 111202266 111208734

BOE:	106307075 106308144 106315314 106335868

RSZ:	108805986 108822723 130506840

THJ:	104807732 104824831

CPAP:

110812918

CIT:	102611797 102612388 102621651

CIC:	CICLE_v10000379mg CICLE_v10027252mg CICLE_v10030727mg

PVY:	116132933 116132979 116141402 116141403

MINC:

123198525 123211731

TCC:

18611720

GRA:	105785380 105787887

GHI:	107890889 107922452 107925060 107950594

GAB:	108461317 108474030

HSYR:

120163530 120174400 120184586

DZI:	111292457 111315727

EGR:

104415850

RARG:

115727830 115729949

GMX:	100791639 547948 548020

GSJ:	114410129 114413190 114415738

PVU:	137812454 137821434

VRA:	106752721 106773132

VAR:	108323826 108348006

VUN:	114179589 114196175

VUM:	124846402 124847975

CCAJ:

109797689 109799467

APRC:

113846685 113871171

MTR:	11438405 25488510

TPRA:

123917454

CAM:	101505566 101511040

PSAT:

127086811 127101086

VVO:	131602813 131639372 131656175 131657944

LJA:	130711730 130713635

ADU:

107480342

AIP:

107630954

AHF:	112733176 112791190

LANG:

109337653 109360372 109361590

PCIN:

129309060

QSA:	O6P43_023312

FVE:

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103401829 103418293

MSYL:

126604459 126627882

PXB:

103961828

PCOX:

137720282 137734172

ZJU:	107408486 107425514

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

111452947 111452987 111463501

CPEP:

111782127 111803152 111803311

RCU:	8262003 8283227

MEAN:

126656026

JCU:	105635495 105636584

HBR:	110636416 110654665 110665474

MESC:

110607134 110628467

POP:	7457154 7469236 7486350

PEU:	105123894 105126394 105139498

PALZ:

118038941 118049636 118061811

PNZ:	133672294 133693946 133695389

JRE:	108980341 109009987 109011399

CILL:

122295574 122303494 122307173

CAVE:

132165788 132184063

AGLU:

133857768 133867349

QSU:	112027508 136066507

QLO:

115994875

TWL:	119992100 120008415

VVI:

100261117

VRI:

117918967

SLY:	101249065 101263997

SPEN:

107015598 107017905

SOT:	102585367 102602086

SSTN:

125855009 125855430

SDUL:

129870787 129901606

CANN:

107851497 107853911

LBB:	132613890 132614000

NTA:	107770366 107803584 107807190(RNR1b) 107829206

NSY:	104245038 104246768

NTO:	104091603 104111756

NAU:	109238566 109242226

INI:	109172549 109174761

ITR:	116011824 116020920

SIND:

105171121

OEU:	111366817 111373014 111377259

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:	110878239 110912757

ECAD:

122605868

LSV:	111882479 111918906

CCAV:

112515319

DCR:	108212642 108214210

CSIN:

114258763 114296021 114315016

RVL:

131303241

AEW:	130777628 130780286

DLT:	127803541 127803542 127803543 127803544

BVG:

104895476

SOE:	110792679 110794252

CQI:	110682052 110695212

ATRI:

130820166

MOF:

131160456

NNU:	104589604 104599944

MING:

122072002 122074597

TSS:	122648812 122669235

PSOM:

113283524 113287118 113357203

OSA:	4331059 4340258

DOSA:

Os06g0168600

OBR:	102705882 102712823

OGL:	127761118 127777659

BDI:	100839518 100844446

ATS:	109742339 109759604

TDC:	119318408 119323951 119327936 119336372

TAES:

123128868 123139376 123146011 123149004 123153637 123156757 123165206

TUA:

125520406

LPER:

127305496 127318051

LRD:	124669991 124681805 124688827 124688835

SBI:	8070903 8084665

ZMA:	100502278 110017794

MFLO:

136475146 136520108 136527263

SITA:

101769230 101770596 101777285

SVS:	117841447 117853118 117858470

PVIR:

120645405 120657530 120669041 120669958 120702745

PHAI:

112890968 112895156

PAUA:

133926322 133930789

PDA:	103704373 103723272 103723590 120107510

EGU:	105038036 105041246 105048410

MUS:	103971825 135615105

ZOF:	121988619 121991862 121992211 121996149 121997500 122038993

DCT:	110104785 110107491

PEQ:	110026919 110027962

AOF:	109833689 109836553

MSIN:

131225021 131236137 131242469

ACAK:

137955627

NCOL:

116244989 116265082 116266988

ATR:

18436844

CJF:	131035219 131057395

SMO:	SELMODRAFT_109545 SELMODRAFT_156827

PPP:	112282398 112283617

CRE:	CHLRE_12g492950v5

VCN:	VOLCADRAFT_82353

MNG:	MNEG_13580

CSL:	COCSUDRAFT_54521

CVR:	CHLNCDRAFT_32953

APRO:

F751_4412

OLU:	OSTLU_48569

OTA:	OT_ostta01g00090

BPG:	Bathy01g00140

MIS:	MICPUN_93299

MPP:	MICPUCDRAFT_31349

CME:	CYME_CMM323C

GSL:	Gasu_24710 Gasu_63390

CCP:	CHC_T00008926001

SCE:	YER070W(RNR1) YIL066C(RNR3)

SEUB:

DI49_1474 DI49_2718

SPAO:

SPAR_E01450 SPAR_I00980

AGO:	AGOS_ACR155W AGOS_ADL057W

ERC:	Ecym_4318 Ecym_8305

KLA:	KLLA0_C07887g KLLA0_F01188g

KMX:	KLMA_50048(RNR1) KLMA_70170(RNR1)

LTH:	KLTH0A04686g KLTH0D09922g

VPO:	Kpol_259p5 Kpol_411p13

ZRO:	ZYRO0C08514g ZYRO0F10956g

CGR:	2889728(GVI51_J02959)

NCS:	NCAS_0A13590(NCAS0A13590) NCAS_0E03350(NCAS0E03350)

NDI:	NDAI_0A02440(NDAI0A02440) NDAI_0E04890(NDAI0E04890)

TPF:	TPHA_0J00970(TPHA0J00970) TPHA_0K00840(TPHA0K00840)

TBL:	TBLA_0C04740(TBLA0C04740) TBLA_0J01350(TBLA0J01350)

TGB:	HG536_0A07150 HG536_0C05050

TDL:	TDEL_0A05600(TDEL0A05600) TDEL_0H01880(TDEL0H01880)

KAF:	KAFR_0B01350(KAFR0B01350) KAFR_0B01360(KAFR0B01360) KAFR_0L01000(KAFR0L01000)

KNG:	KNAG_0C04280(KNAG0C04280) KNAG_0L01620(KNAG0L01620)

ZMK:	HG535_0A03810 HG535_0F03890

SLUD:

SCDLUD_000332

DHA:	DEHA2G05610g DEHA2G23276g

PIC:	PICST_29856(RNR1.1) PICST_75662(RNR1.2)

PGU:	PGUG_02918 PGUG_04094

SPAA:

SPAPADRAFT_49208 SPAPADRAFT_60812

LEL:	PVL30_001273(RNR1) PVL30_002779

LBG:	92206827(LODBEIA_P16310) 92209833(LODBEIA_P46370)

CAL:	CAALFM_C203160CA(RNR1) CAALFM_CR05570CA(RNR3)

CTP:	CTRG_00587 CTRG_01309

COT:	CORT_0A11030 CORT_0D04620

CDU:	CD36_17930 CD36_30920

CTEN:

18245529(RNR1) 18249900(PSN45_000446)

CLU:	CLUG_01593 CLUG_02459

CLUS:

A9F13_13g00308 A9F13_28g00429

CAUR:

CJI96_0003902 CJI96_0004550

ASAU:

88171204(PUMCH_000135) 88173137(PUMCH_002072)

PPA:	PAS_chr1-1_0282 PAS_chr2-1_0209

PKZ:	C5L36_0A12560 C5L36_0D03490

BNN:	FOA43_000126(RNR1) FOA43_002267

BBRX:

BRETT_000971(RNR1) BRETT_005042

OPA:	HPODL_01654 HPODL_04149

YLI:	2908285(YALI2_E00863g) 2910570(YALI2_D01065g)

SLB:	AWJ20_1616(RNR1) AWJ20_3212(RNR1)

NCR:	NCU03539(un-24)

NTE:	NEUTE1DRAFT123455(NEUTE1DRAFT_123455)

SMP:	10810011(SMAC4_07771)

PAN:	PODANSg6979

PBEL:

QC761_604460(RNR1)

PPSD:

QC762_604460(RNR1)

PPSP:

QC763_604460(RNR1)

PPSA:

QC764_604460(RNR1)

TTT:	THITE_2123125

MTM:	MYCTH_2311451

CTHR:

CTHT_0007080

RTHE:

98127625(VTJ83DRAFT_6287)

MGR:

MGG_07000

PPEI:

PpBr36_07476

PGRI:

PgNI_06089

TMN:	UCRPA7_8211

SSCK:

SPSK_03956

FGR:	FGSG_05174

FPU:	FPSE_06575

FPOA:

FPOAC1_008521(RNR1)

FVN:	FVRRES_09108

FVR:	FVEG_04844

FOX:	FOXG_07921

NHE:	NECHADRAFT_78814

FFC:	NCS54_00532700

FKR:	NCS57_00571000

FMU:	J7337_006880(RNR1)

TRE:	TRIREDRAFT_74047

TRR:	M419DRAFT_139792

TATV:

25780867(TrAtP1_000489)

TASP:

36613536(RNR1)

MAW:	19249913(RNR1)

MAJ:

MAA_08816

MBRN:

26242316(rnr-1)

PCHM:

VFPPC_15251

CMT:

CCM_01863

AMUS:

LMH87_003415

PLJ:	28889015(PLICBS_008510)

PTKZ:

JDV02_006123(RNR1)

VAL:	VDBG_01511

VDA:	VDAG_04045

CFJ:	CFIO01_07462

CLUP:

CLUP02_01003

CHIG:

CH63R_12886

CDET:

87943061(CDEST_06558)

SAPO:

SAPIO_CDS0250

ELA:	UCREL1_2597

PFY:	PFICI_11420

SSL:	SS1G_10937

BFU:	BCIN_04g06740

MBE:

MBM_05003

PSCO:

LY89DRAFT_692414

GLZ:	GLAREA_08727

ANI:	ANIA_04380

AFM:	AFUA_4G06690

ACT:	ACLA_045930

NFI:	NFIA_109530

AOR:	AO090023000916

ANG:	An04g01080

AFV:	AFLA_007271

ALUC:

AKAW2_51140A(RNR1)

ACHE:

ACHE_20567A(RNR1)

APUU:

APUU_70566A(RNR1)

PCS:	N7525_004568

PDP:	PDIP_13460

POU:	POX_h09471

TMF:	EYB26_001248

TRG:	TRUGW13939_03481

CIM:	CIMG_04098

CPW:	9693766(RNR1)

URE:	UREG_06803

ABE:

ARB_02698

TVE:

TRV_05425

PBL:	PAAG_07682

PBN:	PADG_04510

AJE:	HCAG_05637 HCAG_09248

BGH:	BDBG_04864

PNO:	SNOG_04815

PTE:

PTT_14367

PTRR:

6342351(PtrM4_091450)

BZE:	COCCADRAFT_26803

BSC:	COCSADRAFT_33284

BOR:	COCMIDRAFT_6805

AALT:

CC77DRAFT_967266

ADAC:

96084161(ACET3X_003839)

ARAB:

EKO05_0007520

ZTR:	MYCGRDRAFT_101786

PFJ:	MYCFIDRAFT_214917

FFU:	CLAFUR5_13777

CBET:

CB0940_04901

BCOM:

BAUCODRAFT_138578

NPA:	UCRNP2_5331

TML:	GSTUM_00008921001

SPO:	2541695(cdc22)

SOM:	SOMG_04733(cdc22)

CNE:

CNE03330

CNB:

CNBE3330

CNG:	CNAG_02208

CGI:	CGB_E4330W

CDEU:

CNBG_5348

CDEP:

91085291(L203_101077)

KMG:	30160367(I203_104502)

KNE:	92180753(IAR55_003495)

TMS:	TREMEDRAFT_39705

TASA:

A1Q1_04362

CCAC:

CcaHIS019_0308470(RNR1)

TVS:	TRAVEDRAFT_28460 TRAVEDRAFT_41085

DSQ:	DICSQDRAFT_153784

PCO:	PHACADRAFT_261748

SHS:	STEHIDRAFT_105343 STEHIDRAFT_124967

HIR:	HETIRDRAFT_474917

PSQ:	PUNSTDRAFT_107092 PUNSTDRAFT_60855

ADL:	AURDEDRAFT_116331 AURDEDRAFT_147076

FME:	FOMMEDRAFT_128598

GTR:	GLOTRDRAFT_81543

RSX:	RhiXN_09396

LBC:	LACBIDRAFT_176996(LbRNRalpha1)

CCI:	CC1G_03383

ABP:	AGABI1DRAFT58613(AGABI1DRAFT_58613)

ABV:	AGABI2DRAFT223838(AGABI2DRAFT_223838)

PCUB:

JR316_0007391

MRR:	Moror_13577

E1B28_012105(CDC22)

SCM:	SCHCO_02616627(SCHCODRAFT_02616627)

CPUT:

CONPUDRAFT_165419

SLA:	SERLADRAFT_450431

WSE:	WALSEDRAFT_31633

WIC:	J056_004212

UMA:	UMAG_11750

PFP:	PFL1_04570

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_11083

PTRC:

PtA15_6A39

PSTR:

Pst134EA_003422

MLR:	MELLADRAFT_41450

ECU:	ECU10_0920

EIN:	Eint_100860

EHE:	EHEL_100930

ERO:	EROM_100800

NCE:	NCER_100976 NCER_101343

VNX:	VNE69_03074 VNE69_07203

RIE:	OCT59_004138 OCT59_026309

MBR:	MONBRDRAFT_37398

SRE:	PTSG_01558

DDI:	DDB_G0284071(rnrA)

DPP:	DICPUDRAFT_49298

DFA:	DFA_05803(rnrA)

ACAN:

ACA1_119180

PFA:	PF3D7_1437200

PFH:	PFHG_00282

PREI:

PRSY57_1436500

PGAB:

PGSY75_1437200

PLAG:

39744310(PADL01_1437200)

PYO:	PY17X_0614100

PCB:	PCHAS_0613300

PBE:	PBANKA_0611600

PVV:	PVVCY_0601170

PKN:	PKNH_0423900

PVX:	PVX_084685

PCY:	PCYB_132180

PMAL:

PMUG01_13023100

PBRS:

92372955(MKS88_004868)

PREL:

PCOT:

TAN:

TPV:

TOT:	TOT_030000324

BEQ:	BEWA_012000

BBO:	BBOV_I004870

BMIC:

BmR1_04g05880

BBIG:

BBBOND_0405840

CPV:

cgd6_1950

CHO:	Chro.60230

TGO:	TGME49_294640

BBES:

BESB_025960 BESB_026010

PTM:	GSPATT00002416001 GSPATT00006871001

PTI:	PHATRDRAFT_42726 PHATRDRAFT_45529

FCY:	FRACYDRAFT_260490 FRACYDRAFT_262579

TPS:	THAPSDRAFT_268807(RIR1_2) THAPSDRAFT_370(RIR1_1)

AAF:	AURANDRAFT_30730(RRL2) AURANDRAFT_37557(RRL1) AURANDRAFT_54285(RRL5)

PSOJ:

PHYSODRAFT_246827

SPAR:

SPRG_04116

TBR:	Tb11.02.5720

TBG:	TbgDal_XI8940

TCR:	504073.30 506933.20

LMA:	LMJF_28_0890

LIF:	LINJ_28_0980

LDO:	LDBPK_280980

LMI:	LMXM_28_0890

LMAT:

92513171(LSCM1_03107)

LBZ:	LBRM_28_0960

LPAN:

LPMP_280950

LOI:	92359761(LSCM4_03832)

LEIS:

94179412(GH5_03956)

LENR:

94171664(CUR178_04446)

LEIN:

94186737(JIQ42_03049)

PHET:

94289588(JKF63_03509)

EHX:	EMIHUDRAFT_449248

GTT:	GUITHDRAFT_100891

VG:

11107192(YKV052c) 11266471(CyHV3_ORF141) 11536503(orf47) 14011284(CyHV1_ORF141) 14011370(CyHV2_ORF141) 1485960(CPXV083_CDS) 1486459(K4L) 15009940(CGPG_00042) 16489537(Hsp137) 18559033(CJ95_gp159) 22220427(F778R) 22619740(SB15_gp150) 22974508(ORF-141) 24170833(ZX48_gp005) 24528103(ACG19_gp069) 26040121(rr1) 26100772(AR677_gp032) 26100856(AR677_gp116) 2715800(SenVgp142) 29057650(BIZ96_gp072) 29064019(BI079_gp072) 30344144(OS5_330R) 33867995(CKM52_gp069) 33868198(CKM51_gp065) 33899775(CG743_gp049) 3431512(ORF-151_RR1) 3707606(I4L) 37628548(D1P95_gp020) 3974395(ASNV_gp153) 40525787(NYs-1_863R) 40527090(FLA65_gp158) 41332292(FK951_p1220) 41699925(EXJ75_gp130) 41900578(CVA-1_929L) 41901094(F778R) 41901254(F778R) 41901416(F778R) 41901584(BA71V-F778R) 41901750(BA71V-F778R) 41901908(F8213_gp048) 41902095(F778R) 41902307(F778R) 41902462(F778R) 41902627(BA71V-F778R) 4238743(TATV_DAH68_076) 5142039(TNSV_gp144) 5176469(EONV_gp126) 5364426(N766L) 5470577(Z101L) 5659976(C748R) 5850529(rr1) 59226995(F778R_CDS) 6295472(rr1) 65100601(KM542_gp080) 65100816(KM543_gp074) 65101619(rr1) 65101716(rr1) 65102245(KM664_gp126) 6804879(FeldSpV_gp096) 6965931(AgipMNPV_gp163) 72551475(OPG080) 7804581(EupsNPV_gp126) 917948(A629R) 920756(ORF180) 922130(SlnVgp023) 929053(OPG080) 932440(SPV042) 932637(CamMLVgp071) 935831(rr1) 951580(EVM057) 951822(rr1) 955124(orf95)

» show all

Reference

PMID:16376858

Authors

Qiu W, Zhou B, Darwish D, Shao J, Yen Y

Title

Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.

Journal

Biochem Biophys Res Commun 340:428-34 (2006)
DOI:10.1016/j.bbrc.2005.12.019

Sequence

[hsa:6240]

Reference

PMID:11893751

Authors

Domkin V, Thelander L, Chabes A

Title

Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.

Journal

J Biol Chem 277:18574-8 (2002)
DOI:10.1074/jbc.M201553200

Reference

PMID:22436573

Authors

Valsecchi ME, Holdbrook T, Leiby BE, Pequignot E, Littman SJ, Yeo CJ, Brody JR, Witkiewicz AK

Title

Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?

Journal

BMC Cancer 12:104 (2012)
DOI:10.1186/1471-2407-12-104

LinkDB

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