About: ERG11

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ERG11 or Sterol 14-demethylase is a fungal cytochrome P450 enzyme originally from Saccharomyces cerevisiae, belongs to family CYP51, with the CYP Symbol CYP51F1. ERG11 catalyzes the C14-demethylation of lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol which is the first step of biosynthesis of the zymosterol, zymosterol will be further converted into Ergosterol.

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  • ERG11 or Sterol 14-demethylase is a fungal cytochrome P450 enzyme originally from Saccharomyces cerevisiae, belongs to family CYP51, with the CYP Symbol CYP51F1. ERG11 catalyzes the C14-demethylation of lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol which is the first step of biosynthesis of the zymosterol, zymosterol will be further converted into Ergosterol. (en)
  • ERG11或甾醇-14-去甲基酶(Sterol 14-demethylase)是一种真菌细胞色素P450酶,最初发现于酿酒酵母(Saccharomyces cerevisiae)基因组,属于CYP51家族,代号CYP51F1。ERG11催化羊毛甾醇转化为酵母甾醇的第一步,羊毛甾醇的14α-去甲基化生成4,4-二甲基-5α-胆甾-8(9),14,24-三烯-3β-醇,酵母甾醇会进一步生成麦角固醇。 (zh)
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dbp:altsymbols
  • CYP51F1 (en)
dbp:chromosome
  • VIII (en)
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  • 1.140000 (xsd:double)
dbp:entrezchromosome
  • NC_001140 (en)
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  • 55488 (xsd:integer)
dbp:name
  • Sterol 14-demethylase (en)
dbp:organism
  • Saccharomyces cerevisiae (en)
dbp:refseqmrna
  • NM_001179137 (en)
dbp:refseqprotein
  • NP_011871 (en)
dbp:symbol
  • ERG11 (en)
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  • 4932 (xsd:integer)
dbp:uniprot
  • P10614 (en)
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rdfs:comment
  • ERG11 or Sterol 14-demethylase is a fungal cytochrome P450 enzyme originally from Saccharomyces cerevisiae, belongs to family CYP51, with the CYP Symbol CYP51F1. ERG11 catalyzes the C14-demethylation of lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol which is the first step of biosynthesis of the zymosterol, zymosterol will be further converted into Ergosterol. (en)
  • ERG11或甾醇-14-去甲基酶(Sterol 14-demethylase)是一种真菌细胞色素P450酶,最初发现于酿酒酵母(Saccharomyces cerevisiae)基因组,属于CYP51家族,代号CYP51F1。ERG11催化羊毛甾醇转化为酵母甾醇的第一步,羊毛甾醇的14α-去甲基化生成4,4-二甲基-5α-胆甾-8(9),14,24-三烯-3β-醇,酵母甾醇会进一步生成麦角固醇。 (zh)
rdfs:label
  • ERG11 (en)
  • ERG11 (zh)
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