The 1941 VMI Keydets football team was an American football team that represented the Virginia Military Institute (VMI) as a member of the Southern Conference during the 1941 college football season. In its fifth season under head coach Pooley Hubert, the team compiled a 4–6 record (4–2 against conference opponents), tied for fifth place in the conference, and was outscored by a total of 173 to 134. The team played its home games at Alumni Field in Lexington, Virginia, and Municipal Stadium in Lynchburg, Virginia.