L-thyroxine (T4) is indicated for the treatment of myxoedema coma in adult patients.

Subjects not fulfilling the above inclusion criteria at the time of interview and/or with congenital disorders, mental disorders, endocrine disorders (e.g., Myxoedema), Cushing's syndrome, and metabolism disorders (diabetes mellitus), CVD, heart failure, and pregnant women were excluded.

In rare cases, a very underactive thyroid can lead to a life-threatening condition called myxoedema, causing drowsiness, confusion and hypothermia.

Low concentrations are found in myxoedema, hyperprolactinemia, and syndromes of excessive androgen activity.

Nielsen, "Spinal bone mineral content in myxoedema and thyrotoxicosis.

Myxoedema and secondary cutaneous amyloidosis, rare complications of RA, were also not confirmed.

He noticed however the patient developed myxoedema, which he called 'Cachexia strumipriva.' Initially, he used vertical skin incision, later changed to transverse collar incision, which is usually associated with his name.

Myxoedema crisis is an almost forgotten cause of multiorgan failure with a mortality of about 25-50% [1, 2].

Morris, "Iatrogenic myxoedema madness following radioactive iodine ablation for Graves' disease, with a concurrent diagnosis of primary hyperaldosteronism," Endocrinology, Diabetes & Metabolism Case Reports, vol.

[2] Their dysfunction manifests in a wide spectrum of clinical diseases and biochemical abnormalities, from clinically intangible diseases to myxoedema coma.

Hyperthyroidism with periodic paralysis, acropachy, pre-tibial myxoedema, transient atrial fibrillation and myopathy.

It is contraindicated in cardiovascular diseases serious hepatic and renal dysfunction, mysthenia gravis, neuro muscular diseases, myxoedema, adrenocortical insufficiency, extreme age and asthma.