Vestibular nuclei and nucleus tractus solitarii send ascending neurons to prosencephalon. Nucleus tractus solitarii sends axons directly to amygdala, thalamus, basal forebrain (bed nucleus of the stria terminalis), hypothalamic nuclei [98, 99], and the paraventricular thalamic nucleus.

In anamniotes, the prosencephalon contains an array of tracts and commissures, such as the anterior commissure (AC), supraoptic commissure (SOT), postoptic commissure (POC), and tract of the postoptic commissure (TPOC).

It is characterised by failure of cleavage of the prosencephalon, a process that usually occurs between the 18th and 28th days of gestation.

Holoprosencephaly (HPE) occurs as a result of a failure of cleavage, septation, or differentiation of the prosencephalon, which is the portion of the embryonic brain that later differentiates into the cerebrum, basal ganglia, and thalamic structure.

This forebrain neurodegeneration depletes cholinergic projections in virtually the entire prosencephalon. Specifically, degeneration of the Nucleus Basalis of Meynert as well as the medial septum severely perturbs cholinergic neurotransmission at the level of the cortex and hippocampus, respectively [3].

The holoprosencephalies are a group of disorders that develop as a result of abnormal differentiation and cleavage of the prosencephalon. Holoprosencephalies are commonly divided into three subcategories based on severity: alobar, semilobar, and lobar.

For an umbrella term, I am satisfied with the general dictionary definition of cerebral, which describes it as pertaining to the brain without dealing with the finer distinctions between the prosencephalon, mesencephalon, and diencephalon.