The presented activity of first compound was the most probably due to occurrence of two alkyl groups, at third and fifth positions of aniline ring, that of second and third compounds was credibly due to the presence of two alkyl groups at 3rd/5th of position of aniline ring and benzyl group, along with benzyl and ethyl group respectively attached to nitrogen of sulfonamide.

One proton at C-7 appeared as multiplet while the methylene protons of benzyl groups resonated as doublets in the region of 3.11 ppm and 4.0 ppm showing geminal coupling constant of 13.2 Hz.

Benzyl group substituted at N-atom of the parent sulfonamide demonstrated a multiplet ranging at d 7.24-7.22 for 3Hs positioned at 3'' to H-5'' and another multiplet appeared at d 7.14-7.13 having integration of 2Hs positioned at 2'' and 6''.

Further, it's [.sup.1]H NMR spectrum showed a multiplet at 6.86-7.29 ppm due to aromatic protons and a singlet at 5.04 ppm that corresponds to--OC[H.sub.2] of benzyl group. Furthermore, the peaks at 4.22-4.27 ppm as quartet and 1.22-1.26 ppm as triplet indicated the presence of--C[H.sub.2] and--C[H.sub.3] of ester group, respectively.

The overall 3-dimensional shape, however, is similar to desmosterol except for the presence of the large benzyl group at position 3.

In the aliphatic region of the spectrum a singlet appeared at d 4.69 for methylene protons of benzyl group positioned at 7", a multiplet resonated at d 4.38-4.32 having integration of 4Hs positioned for CH2-2 and CH2-3 protons.

1, it is suggested that the affinity between the ABS and clay which contains benzyl group is better than that of the PP and clay because of the high polarity of the ABS compared that of the PP.

From these results, when the Taft equation, log [Kappa]/[[Kappa].sub.0] = [[Zeta].sup.*][[Sigma].sup.*] ([Kappa], degree of alkylation; [[Kappa].sub.0], degree of methylation; [[Zeta].sup.*], reaction constant of Hammet; [[Sigma].sup.*], substituted group constant of Taft), was applied to this substitution reaction, a linear relationship was obtained between log [Kappa]/[[Kappa].sub.0] and [[Sigma].sup.*] except for the benzyl group as shown in Fig.

3), which are probably due to the uncondensed -OH and benzyl groups. The FT-IR spectra of the T_S15 and T_S25 show a large band centred around 3200 [cm.sup.-1] due to the stretching vibration of the -OH on the particles surface and related bending at 1600 [cm.sup.-1], whereas below 900 [cm.sup.-1] the typical broad band due to Ti-O-Ti vibrations was observed [23].