In this 28-day Non-IND, IRB-approved double-blind, randomised, placebo-controlled pilot clinical study, AXA2678 was assessed for safety, tolerability and its effects on muscle structure and function in healthy subjects with immobilization-induced acute muscle atrophy.

The walkathon is an important awareness initiative as we continue to fight multiple system atrophy," said Ritje Schouppe-Moons, Chief Executive of the AMS-MSA Belgium, organizer of the yearly "JiePie Award for MSA Research" and Spokesperson for World MSA Day, observed on October 3rd.

Impact of vulvovaginal health on postmenopausal women: a review of surveys on symptoms of vulvovaginal atrophy. Int J Womens Health.

There are a few ways to treat that atrophy, but Allen learned about a new one at a urogynecology conference in October 2017.

Optic Atrophy refers to damage to, or degeneration of the optic nerve due to any cause.

Secondary lesions were detected in cases with corpus callosum abnormality, atrophy, encephalomalacia and hydrocephaly.

Hirayama disease is a rare condition characterised by a symmetric muscle weakness and atrophy in the C8-T1 distribution with a self-limiting course.

One example is evidence from the CATT (3) trial which suggests a relationship between long-term anti-VEGF therapy and the development of geographic atrophy. The IVAN (4) and HARBOR (6) trials were also retrospectively analyzed in terms of this possible relationship and reported suspicious findings similar to those found in the CATT trial.

Multiple system atrophy (MSA) is an adult onset, progressive, idiopathic neurodegenerative disease that clinically manifest as MSA-C with cerebellar signs predominant, MSA-P with Parkinsonian features predominant and MSA-A with autonomic signs and symptoms.

Extensive macular atrophy with pseudodrusen (EMAP) is a rare clinical entity that was first described by Hamel et al.

Parry-Romberg Syndrome (PRS), also called as Progressive hemifacial atrophy, was first described by Caleb Parry in 1825 and later by Moritz Romberg in 1846 (1).

Three Non-Hormonal Options for Vulvovaginal Atrophy

The C12orf65 gene is a nuclear gene that encodes a mitochondrial matrix protein contributing to mitochondrial translation.[sup][1] C12orf65 gene-related diseases are rare and present with large heterophenotypes.[sup][1],[2],[3],[4] Most of the reported patients have had optic atrophy with intellectual disability, encephalomyopathy, spastic paraplegia, and ophthalmoplegia.[sup][1],[2],[3] Peripheral neuropathy has been reported in one family.[sup][3] Here, we report a case of a Chinese patient with optic atrophy and distal motor neuropathy due to a novel compound heterozygous mutation in the C12orf65 gene.