F (Apresoline); minoxidil (Loniten) Angiotensin II receptor blockers: valsartan (Diovan); Iosartan ?

Table 2 Drugs for Hypertensive Urgencies[6,11] Drug Dosage range CNS effects Alpha blocker 0.2 mg initially Some studies show an Clonidine then 0.1 mg every increase in CBF (by hydrochloride hour to total 28%); can cause (Catapres) of 0.8 mg orally decreased mentation ACE Inhibitor 6.25-25 mg orally Not documented captopril (Capoten) Direct vasodilator 5-10 mg orally Not documented minoxidil (Loniten) Nursing Drug Implications Alpha blocker Rapidly absorbed: Clonidine can cause rebound hydrochloride hypertension when (Catapres) abruptly discontinued ACE Inhibitor Drop in BP within captopril minutes; maximum (Capoten) drop in 30-90 minutes Direct vasodilator Watch for severe minoxidil (Loniten) rebound hypertension reflex tachycardia and fluid retention