Graves' disease is the most common cause of hyperthyroidism, representing approximately 50% to 80% of cases.

Misdiagnosis of Graves' disease with apparent severe hyperthyroidism in a patient taking biotin megadoses.

Graves' disease (GD) is the most common cause of thyrotoxicosis in childhood (2).

As part of the campaign, TEAMeD has devised early warning cards for patients with Graves' disease for them to be aware of symptoms of TED if they should go on to develop it later.1819 Practitioners may wish to discuss this aspect with patients who have a known diagnosis of Graves' disease.

Serum vitamin D levels are decreased and associated with thyroid volume in female patients with newly onset Graves' disease. Endocrine 2012; 42: 739-41.

Our study consisted of 50 patients with hyperthyroidism between age group of 20 - 60 years included Graves' disease and Thyroiditis (1: 1).

Results: We identified PHT at 47.6% of the patients with Graves' disease. Once the euthyroidism status is obtained, PHT is normalized.

Risk factor analysis revealed that gender (p=0.008), marital status (p<0.001), education (p<0.001), smoking (p<0.001), tri-iodothyronine (P <0.001), thyroxin (p<0.001) and thyroid-stimulating hormone (p<0.000) levels in blood were associated with Graves' disease.

Although its pathogenic role remains under debate, calsequestrin has emerged as a new sensitive and specific biomarker of ophthalmopathy in patients with Graves' disease [6, 7].

In a multicentre retrospective analysis of 557 consecutive patients who underwent thyroidectomy for Graves' disease, the overall prevalence of nodule was 25.1% [2].

Graves' disease (GD) is an autoimmune thyroid disease that involves [1, 2] autoreactivity against thyrocytes by antibodies, lytic granules released from cytotoxic T-lymphocytes (CTLs), and apoptosis and the inappropriate presence of death receptors that activate apoptotic pathways [3-5].

However, we wish to bring out a missing point in the review related to an uncommon complication that may occur during the treatment of neonatal Graves' disease. The treating physician needs be cautious of this life-threatening complication, which may occur after initiating antithyroid drugs in the neonate.

According to our results, GPR compared to HR provides better assessment of the protrusion in Graves' disease. GPR measurement is simple and should always be part of the radiological assessment of orbits in Graves' disease.