Sodium periodate
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IUPAC name
sodium periodate
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Other names
sodium metaperiodate
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.029.270 |
EC Number |
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PubChem CID
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RTECS number |
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CompTox Dashboard (EPA)
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Properties | |
NaIO4 | |
Molar mass | 213.8918 g/mol |
Density | 3.865 g/cm3 |
Melting point | 300 °C |
soluble | |
Related compounds | |
Other anions
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sodium perchlorate, sodium perbromate |
Other cations
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potassium periodate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Sodium periodate is the sodium salt of periodic acid. It can refer to two different chemical compounds, sodium metaperiodate (often abbreviated as m-periodate), which has the formula NaIO4, and sodium orthoperiodate (often abbreviated as o-periodate), which has the formula Na5IO6. Both salts are useful in certain synthetic chemistries for the oxidative power of the periodate ion.
Properties
Density is 3.865 g cm−3. It is soluble in water. When heated, it decomposes to form sodium iodate (NaIO3) and oxygen. This decomposition reaction is catalyzed by the presence of manganese(IV) oxide.
Uses
Sodium periodate is used to oxidize cellulose and create a biocompatible and biodegradable compound that can be used as suture, as a scaffold for tissue engineering, or for drug delivery.
Sodium periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups. This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin. Because the process requires vicinal diols, periodate oxidation is often used to selectively label RNA (ribose has vicinal diols) instead of DNA as deoxyribose does not have vicinal diols.