(a) Data set Training Validation Test Normal 728 81 203 Echinocyte 226 25 63 Dacrocyte 64 7 18 Schistocyte 546 61 152 Elliptocyte 66 7 18 Acanthocyte 120 13 33 Target cell 523 58 145 Stomatocyte 79 9 22 Spherocyte 173 19 48 Overlap 166 18 46 (a) Cells were randomly distributed 80:20 between training and test sets, respectively.

(Figures 1, 2) Also on day-2, erythrocytes began to show poikilocytosis with crenated forms and cytoplasmic spikes (burr cells, echinocytes).

morphological alteration of erythrocytes, characterized by the formation of echinocytes and spherocytes and such changes were not seen in the control group (figure 1A and B).

1A, modified erythrocytes, such as spherocytes, cup-shaped cells and echinocytes were ubiquitous in the blood of septic patients but absent in volunteers (Fig.

The number of spherocytes was reduced, whereas other pathological forms of erythrocytes related to reversible forms such as stomatocytes and echinocytes were more frequent (Figure 1(d)) in the patient group after the treatment.

Morphology of RBCs was altered showing poikilocytosis, anisocytosis and presence of prominent echinocytes (Fig.3).

The increased intracellular sodium concentration affects cell volume and causes edema.[sup][5] After prolonged storage, RBC change shape from a normal biconcave disk to echinocytes and Spheroechinocytes.

In addition, the vast majority of erythrocytes in the sample were also crenated (abnormally shaped, echinocytes, or burr cells, Fig.