Other treatments such as oral medication that includes anticholinergic agents and dopaminergic agents are used in combination.

Myocardial Infarction (MI), ventricular reentry arrhythmias etc.2,3 Medications like CNS depressants, antipsychotics, Tricyclic Antidepressants (TCA), selective serotonin reuptake inhibitors (SSRIs), 4 Non-Steroidal AntiInflammatory Drugs (NSAIDs) and anticholinergic agents are associated with increased risk of falling (50%), hip fracture, gastrointestinal bleeding, cognitive impairment and functional decline.5

Those six include long-acting sedative hypnotics, including diazepam (Valium); loop diuretics; and anticholinergic agents, including sedating antihistamines, antipsychotics, tricyclic antidepressants, and tiotropium bromide (Spiriva).

Currently available interventions include aluminum chloride, which often helps insufficiently or is irritating; systemic anticholinergic agents, which can have intolerable side effects like dry mouth; or botox injections, which are temporary, painful, and expensive.

MG is a neuromuscular disorder that can be triggered by anticholinergic agents [2].

(4,5) Medications are second-line treatments for OAB, after non-pharmacological options, with disease management generally relying on the use of anticholinergic agents. (6) Currently in Canada there are six anticholinergic drugs approved for treatment of OAB symptoms: darifenacin, fesoterodine, oxybutynin, solifenacin, tolterodine and trospium.

A 2013 study carried out by the same investigators suggested that the likelihood of developing cognitive impairment increased by 100 percent in people who took one strong anticholinergic agent for more than 60 days, and by 50 percent in those who took at least three mild anticholinergic agents for more than 90 days.

* Anticholinergic agents used to treat conditions such as asthma, gastrointestinal cramps, sleep and depression.

Opiates, interferon, steroids, reserpine, and other drugs can be depressogenic; on the other hand, steroids, anticholinergic agents, and antidepressants can induce mania.

Inhaled medications are preferred either as short-acting or long-acting beta-agonist or anticholinergic agents. Anti-inflammatory agents are added for the more symptomatic or frequently-exacerbating patient.

OAB is treated with anticholinergic agents. (4) Anticholinergic agents affect the human body by inhibiting specific receptors, which is supposed to suppress the permanent or sudden urge to urinate.