backfolding

backfolding

[′bak‚fōld·iŋ]
(geology)
Process in mountain forming in which the folds are overturned toward the interior of an orogenic belt. Also known as backward folding.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The binding ability of dendrimers to siRNA strongly depended on the dendrimer generation and the pH value related to backfolding. G4 dendrimer exhibited excellent adaptability to siRNA while G6 behaved like a rigid sphere with a loss in the binding affinity.
Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization.